Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1993-09-28
1995-07-18
Chan, Nicky
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514570, 514569, 514568, 514544, 514533, 514532, 514522, 514602, 514604, 514616, 514622, 514621, 514671, 558415, 560 12, 560 51, 560 53, 560 54, 562461, 562462, 562427, 564169, 564162, 564156, 564154, A61K 3119, A61K 31235, A61K 31165, C07C23532, C07C 6304, C07C 6978, C07C25549
Patent
active
054341868
ABSTRACT:
Compounds of the formula ##STR1## wherein X is O or CH.sub.2 ; Y is O, --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, or --OCH.sub.2 C.sub.6 H.sub.4 --;
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patent: 4889871 (1989-12-01), Djuric et al.
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Brown, F. J. et al.--Hydroxyacetophenone--Derived Antagonists of the Peptidoleukotrienes--J. Med. Chem. 1989, 32, 807-826.
Gapinski, D. M. et al--Benzophenone Dicarboxylic Acid Antagonists of Leokotriene B.sub.4 --J. Med. Chem. 1990, 33, 2807-2873.
Konno, M. et al--Synthesis and Structure--Activity Relationships of A Series of Substituted--Phenylpropionic Acids--Advanced in Prostaglandin Thromboxane and Leukotriene Res. vol. 21, 411-413 (1990).
Communications-7-3-(4-acetyl-3-methoxy-2-propylphenoxy)pro poxy-3,4-dihydro-8-propyl-2H-1-benzopyran-2-carboxylic acid--J. Med. Chem. 1989, vol. 32, No. 6, 1145-1147.
Cohen Noal
Lee Ferdinand K.
Yagaloff Keith A.
Chan Nicky
Gould George M.
Hoffmann-La Roche Inc.
Johnston George W.
Silverman Robert A.
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