Carboxylic acid derivatives that inhibit the binding of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S345000, C514S349000, C546S183000, C546S290000, C546S296000, C546S297000

Reexamination Certificate

active

07812038

ABSTRACT:
A method for the inhibition of the binding of α4β1integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which α4β1is involved.

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