Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ortho-hydroxybenzoic acid or derivative doai
Reexamination Certificate
2006-06-06
2006-06-06
Wilson, James O. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ortho-hydroxybenzoic acid or derivative doai
C514S163000, C514S166000, C562S430000, C562S433000, C562S434000, C562S435000, C562S437000
Reexamination Certificate
active
07056903
ABSTRACT:
This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I:wherein:R1, R2, and R3are each independently in each occurrence aryl or heteroaryl;R4is —COOH or tetrazolyl;A, B, m, n, and r are as defined in the specification;or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and processes for their preparation.
REFERENCES:
patent: 5250517 (1993-10-01), Branca et al.
patent: 5610176 (1997-03-01), Horwell et al.
patent: 5981755 (1999-11-01), Horwell et al.
patent: 6221907 (2001-04-01), Bernard et al.
Hcaplus 100:210433.
Cournoyer Richard Leo
Keitz Paul Francis
Lowrie, Jr. Lee Edwin
Muehldorf Alexander Victor
O'Yang Counde
Hall Robert C.
Robinson Binta
Syntex (U.S.A.) LLC
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