Carboxylic acid derivative

Details Carboxylic acid derivative Carboxylic acid derivative

1993-03-23

1995-05-30

Chang, Celia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514354, 514355, 514356, 514357, 546309, 546310, 546337, 546323, 546322, A61K 3144, A61K 31445, C07D21340, C07D21346

Patent

active

054201454

ABSTRACT:
Carboxylic acid derivatives having potent retinoid-type pharmacological activities are disclosed. The compounds disclosed are represented by the following formula: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 independently represent a hydrogen atom or an alkyl group with the exception that all of R.sup.1, R.sup.2, and R.sup.3 do not simultaneously represent hydrogen atoms and R.sup.1 together with R.sup.2 optionally represent a cyclic structure formed by the combination thereof; R.sup.4 represents a hydrogen atom or an alkyl group; X represents a nitrogen atom or C--OH; and A represents --CO--NH-- or --NH--CO--.

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