Carboxylic acid amide compounds and their derivatives

Details Carboxylic acid amide compounds and their derivatives Carboxylic acid amide compounds and their derivatives

1984-06-12

1986-06-24

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

562455, 562442, 548513, 514417, C07C101453, A61K 31195

Patent

active

045968268

ABSTRACT:
Described herein are novel carboxylic acid amide compounds or carboximide compounds represented by the general formula: ##STR1## wherein Z represents a group of the formula (1) or (2): ##STR2## wherein R.sup.1 and R.sup.2 are hydrogen atom or methyl group, respectively; Xs, which may be the same or different, are hydrogen atom, a lower alkyl, lower alkoxy, halo, or alkyl halide group, respectively, and n represents an integer of 0 to 2, and their pharmaceutically acceptable salts; process for the production thereof; and medicines containing the same. The novel compounds are useful as treating, preventing and improving agents for diseases attended with cerebral dysfunction as well as various symptoms caused by the said diseases. Further, the compounds are useful for the improvement of neurosis of the stomach; and treatment and prevention for various constipation.

REFERENCES:
patent: 3507904 (1970-04-01), Schwartz et al.
patent: 3654302 (1972-04-01), Schwartz et al.
patent: 3745170 (1973-07-01), Fujinami et al.
patent: 3987056 (1976-10-01), Cobb
patent: 4002460 (1977-01-01), Pallos
patent: 4361576 (1982-11-01), Buhler et al.
patent: 4409018 (1983-10-01), Ishida

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