Carboxyl- or hydroxyl-substituted benzimidazole derivatives

Details Carboxyl- or hydroxyl-substituted benzimidazole derivatives Carboxyl- or hydroxyl-substituted benzimidazole derivatives

2008-12-10

2010-10-19

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S394000

Reexamination Certificate

active

07816540

ABSTRACT:
This invention relates to novel carboxyl- or hydroxyl-substituted benzimidazole derivatives of formula (I)wherein R1to R6are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.

REFERENCES:
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patent: WO 2007/081335 (2007-07-01), None
patent: WO 2008/000643 (2008-01-01), None
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Larock, R.C., Comprehensive Organic Transformations, 2ndEdition, John Wiley & Sons, New York, NY, pp. 1941-1949 (1999).

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