Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-03-23
1989-02-28
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514423, 548553, 548492, A61K 3140, C07D20716
Patent
active
048085731
ABSTRACT:
The present invention relates to carboxyalkyl dipeptides which are inhibitors of angiotensin-converting enzyme and are useful as antihypertensive agents and in the treatment of congestive heart failure.
The compounds of the present invention are compounds of the formulae ##STR1## and the pharmaceutically acceptable salts thereof, wherein R and R.sup.6 are the same or different and are hydroxy or lower alkoxy;
REFERENCES:
patent: 4350704 (1982-09-01), Hoefle et al.
patent: 4374829 (1983-02-01), Harris et al.
patent: 4508729 (1985-04-01), Vincent et al.
Gold Elijah H.
Neustadt Bernard R.
Smith Elizabeth M.
Magatti Anita W.
Miller Stephen I.
Nelson James R.
Schering Corporation
Springer David B.
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