Carboxy terminal peptide-extended proteins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 435325, 514 8, 514 2, 514 12, 530395, 530300, 530350, 530399, 536 2351, A61K 3817, C07K 14435, C12N 510, C12N 1512

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057121222

ABSTRACT:
Modified protein pharmaceuticals extended with a CTP unit retain their biological activity and they had extended biological half-lives. The CTP extension represents an amino acid sequence derived from that of positions 112-118 to 145 of human chorionic gonadotropin.

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