Carboxamide derivatives having tetrazole and thiazole rings and

Details Carboxamide derivatives having tetrazole and thiazole rings and Carboxamide derivatives having tetrazole and thiazole rings and

1988-11-28

1990-08-07

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514314, 514342, 546167, 546276, 548195, C07D41712, C07D41744, A61K 31425

Patent

active

049468553

ABSTRACT:
A compound of the formula: ##STR1## wherein the free valency of the groups A-, R- and --X--Y-- is attached to any of 2-, 4- and 5- positions of the thiazol ring, A is a C.sub.1-6 alkyl group, an aryl group which is unsubstituted or substituted with at least one substituent selected from the group consisting of hydroxy C.sub.1-6 alkoxy, aryl-(C.sub.1-6)alkoxy, halo-(C.sub.1-6)alkyl, halogen, and nitro,

REFERENCES:
patent: 4112106 (1978-09-01), Sellstedt
patent: 4146631 (1979-03-01), Ford et al.
patent: 4225610 (1980-09-01), Tarayre et al.
patent: 4432986 (1984-02-01), Erickson
patent: 4526979 (1985-07-01), Peet et al.
patent: 4558059 (1985-12-01), Kawasaki et al.
patent: 4567193 (1986-01-01), Peet et al.
J. Med. Chem. 26, pp. 1499-1504 (1983).
Chem. Abst. 79, (15), pp. 441, No. 92204b.
J. Med. Chem. 26, pp. 1158-1163 (1983).
J. Med. Chem. 29, pp. 538-549 (1986).
J. Med. Chem. 29, pp. 2403-2409 (1986).

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