Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1981-05-18
1982-08-10
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
26032641, A61K 3140, C07D207277
Patent
active
043438130
ABSTRACT:
The compounds of the invention are certain new propenamide and 2-butenamide compounds, having a (4-carboxy-2-oxo-pyrrolidino)phenyl substituent at the 3-position, and certain esters thereof, and certain cyclopropanecarboxamide compounds, having a (4-carboxy-2-oxo-pyrrolidino)phenyl substituent at the 2-position, and certain esters thereof. The compounds of the invention are useful for antagonizing the spasmogenic activity of the slow-reacting substance of anaphylaxis (SRS-A) in a human subject. In particular, the compounds of the invention are useful for preventing and treating certain obstructive airways diseases, notably allergic bronchial asthma, allergic rhinitis and certain skin disorders, in human subjects.
REFERENCES:
patent: 4064264 (1977-12-01), Nelson
Fan Jane T.
Frost Albert E.
Knuth Charles J.
Lumb J. Trevor
Pfizer Inc.
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