Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1987-07-08
1989-04-18
Sneed, H. M. S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
558191, 558192, 558190, A01N 5714, C07F 918
Patent
active
048227803
ABSTRACT:
A carboxamide compound of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X are as defined and pharmaceutically acceptable salts thereof, and composition containing the compound are disclosed.
The compound is useful as a calcium antagonistic agent and an antiinflammatory agent.
REFERENCES:
patent: 3681476 (1972-08-01), Gutman
patent: 4232010 (1980-11-01), Tsukamoto et al.
patent: 4268507 (1981-05-01), Mong
patent: 4309364 (1982-01-01), Bentzen et al.
patent: 4371527 (1983-02-01), Bentzen et al.
patent: 4416877 (1983-11-01), Bentzen et al.
patent: 4626528 (1986-12-01), McHenry
Journal of American Chemical Society, vol. 95(7) p. 2362 (1973) and vol. 98(16) p. 4913 (1976).
Tsuda Yoshiaki
Tsuda Yoshihiko
Otsuka Pharmaceutical Factory Inc.
Pak Chung K.
Sneed H. M. S.
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