Carboxamide amino acid heterobicyclic PAF antagonists

Details Carboxamide amino acid heterobicyclic PAF antagonists Carboxamide amino acid heterobicyclic PAF antagonists

1991-09-16

1993-01-19

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514303, 514394, 514395, 514293, 544236, 546 82, 546118, 5483021, 5483107, 5483104, 5483101, 5483071, 5483064, 5483044, 5483061, C07D47104, C07D23508, A61K 31435, A61K 31415

Patent

active

051807246

ABSTRACT:
Compounds of general formula I; ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, A.sup.1, A.sup.2, B, and X are variables.
These compounds are antagonists of platelet activating factor (PAF) and as such are useful in the treatment or amelioration of various diseases or disorders mediated by PAF.

REFERENCES:
patent: 4804658 (1989-02-01), Manley et al.

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