Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-02-16
1997-01-14
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546155, 546158, C07D215227, C07D21538, A61K 3147
Patent
active
055940064
ABSTRACT:
This invention provides a carbostyril derivative of the formula (1): ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and n are as defined, or its salt. This carbostyril derivative or its salt possess an excellent matrix metalloproteinases inhibitory action.
REFERENCES:
patent: 4599361 (1986-07-01), Dickens et al.
patent: 4692522 (1987-09-01), Parsons et al.
patent: 4996358 (1991-02-01), Handa
Chemical Abstracts, 122:230797, 1994.
Imaoka Takeshi
Motoyama Masaaki
Sakamoto Makoto
Takasu Hideki
Yamamoto Yoshihito
Ivy C. Warren
M. Mach D. Margaret
Otsuka Pharmaceutical Co. Ltd.
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