Carbostyril derivatives and salts thereof, processes for prepari

Details Carbostyril derivatives and salts thereof, processes for prepari Carbostyril derivatives and salts thereof, processes for prepari

1986-04-10

1989-07-04

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544363, A61K 31495, C07D40104

Patent

active

048451002

ABSTRACT:
Carbostyril derivatives and salts thereof having excellent positive inotropic activity, increasing activity of coronary blood flow, as well as hypotensive activity in one hand, and also they do not have substantially increasing activity of heart beat as their characteristic property, as well as they have less side-effects in the central nervous system, such as they have less vomiting effect, decreasing effect in motor function and tremor effect.

REFERENCES:
patent: 4022776 (1977-05-01), Nakagawa et al.
patent: 4022784 (1977-05-01), Nakagawa et al.
patent: 4026897 (1977-05-01), Nakagawa et al.
patent: 4415572 (1983-11-01), Tominaga et al.
patent: 4454130 (1984-06-01), Tominaga et al.
patent: 4468402 (1984-08-01), Tominaga et al.
patent: 4487772 (1984-12-01), Tominaga et al.
"Chemical Abstracts", vol. 98, 1983, col. 98:34510e, (Abstract of Belgium Patent No. 892,148, 8/16/82).
Tominaga et al., "Chemical Abstracts", vol. 106, 198, col. 106(13):102057y, (Abstract of Chem. Pharm. Bull., vol. 34, No. 2, 1986), pp. 682-693.

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