Carbostyril derivatives and salts thereof and pharmaceutical com

Details Carbostyril derivatives and salts thereof and pharmaceutical com Carbostyril derivatives and salts thereof and pharmaceutical com

1992-10-08

1995-07-18

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544363, 544333, 546158, A61K 3147, C07D40112, C07D40302

Patent

active

054341647

ABSTRACT:
Carbostyril derivatives and salts thereof represented by the general formula (1a), including some known compounds, possess activities for inhibiting adhesion of thrombocytes. ##STR1## Z, A, X, R, R.sup.1 and R.sup.2 are defined in the specification. Some carbostyril derivatives having chemical structural formulas similar to those of carbostyril derivatives and salts thereof represented by the general formula (1a) have been known in prior art references, however the above-mentioned pharmacological activities have not been known to the present date.

REFERENCES:
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Burger, "Medicinal Chemistry", Interscience Publishers, N.Y. (1960) 2nd Edition, p. 75.
Nishi et al., Chemical Abstracts, vol. 108, No. 167318 (1988).
Yoshizaki et al., Chemical Abstracts, vol. 91, No. 39479 (1979).

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