Carbostyril derivatives and salts thereof and pharmaceutical com

Details Carbostyril derivatives and salts thereof and pharmaceutical com Carbostyril derivatives and salts thereof and pharmaceutical com

1988-08-16

1991-04-16

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514247, 514248, 514249, 514252, 514255, 514256, 514259, 514269, 514274, 514300, 514307, 514309, 544235, 544236, 544238, 544284, 544298, 544315, 544316, 544319, 544336, 544353, 544354, 544405, 544408, A61K 3147, A61K 31505, C07D40112, C07D40312

Patent

active

050082744

ABSTRACT:
A carbostyril derivative or pharmaceutically acceptable salt thereof represented by the following general formula: ##STR1## wherein Z, A, XN, R, R.sup.1, and R.sup.2 are as defined in the specification. These carbostyril derivatives are useful in pharmaceutical compositions for inhibiting adhesion of thrombocytes.

REFERENCES:
patent: 4277479 (1981-07-01), Nishi et al.
patent: 4329347 (1982-05-01), Muller et al.
patent: 4792561 (1988-12-01), Walker et al.
patent: 4824840 (1989-04-01), Banno et al.
Nishi et al., Chemical Abstracts, vol. 108, No. 167318 (1988).
Yoshizaki et al., Chemical Abstracts, vol. 91, No. 39479 (1979).
Abstract for JP 32471 (4/1/81).
Abstract for JP 156263 (12/2/81).
Abstract for JP 77880 (5/11/83).
Abstract for JP 45414 (4/25/81).
Abstract for JP 59980 (4/9/83).
Abstract for JP 159778 (10/1/82).
Abstract for JP 9780 (1/19/82).
Abstract for JP 154129 (9/22/82).
Abstract for DE 2928583 (1/29/81).
Burger, "Medicinal Chemistry", Interscience Publishers, N.Y. (1960), 2nd Edition, p. 75.
Abstract for JP 54/30183 (3/6/79).
Abstract for JP 54/30180 (3/6/79).

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