Carbostyril derivatives and pharmaceutical composition containin

Details Carbostyril derivatives and pharmaceutical composition containin Carbostyril derivatives and pharmaceutical composition containin

1982-04-07

1984-06-19

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

546157, 546158, 424250, C07D40100, A61K 31495

Patent

active

044554222

ABSTRACT:
Novel carbostyril derivatives and their salts, having antihistaminic effect and central nervous system controlling effect, are represented by the general formula (1), ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group, a phenyl-lower alkyl group, a lower alkenyl group, a lower alkynyl group; A is a group of the formula ##STR2## (wherein R.sup.2 is a hydrogen atom or a lower alkyl group); B is a lower alkylene group; l is 1 when A is a group of the formula ##STR3## or l is 0 or 1 when A is a group of the formula ##STR4## Z is a group of the formula >N--R.sup.3 or ##STR5## (wherein R.sup.3, R.sup.4 and R.sup.5 are as defined herein).

REFERENCES:
patent: 4022776 (1977-05-01), Nakagawa et al.
patent: 4022784 (1977-05-01), Nakagawa et al.
patent: 4026897 (1977-05-01), Nakagawa et al.
patent: 4210753 (1980-07-01), Tominaga et al.
patent: 4223137 (1980-09-01), Yoshizaki et al.
patent: 4234584 (1980-11-01), Lattrell et al.

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