Carbostyril derivatives, and central nervous system controlling

Details Carbostyril derivatives, and central nervous system controlling Carbostyril derivatives, and central nervous system controlling

1982-04-07

1984-07-17

Teoli, Jr., William A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546157, 546158, C07D40100, A61K 31445, A61K 3147

Patent

active

044605935

ABSTRACT:
Novel carbostyril derivatives and their salts are useful as antihistaminic agents and central nervous system controlling agents, represented by the general formula (1), ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group, a phenyl-lower alkyl group, a lower alkenyl group, a lower alkynyl group; A is a group of the formula ##STR2## or a group of the formula ##STR3## (wherein R.sup.2 is a hydrogen atom or a lower alkyl group); B is a lower alkylene group; l is 1 when A is a group of the formula ##STR4## or l is 0 or 1 when A is a group of the formula ##STR5## Z is a group of the formula >N--R.sup.3 or ##STR6## (wherein R.sup.3, R.sup.4 and R.sup.5 are as defined herein).

REFERENCES:
patent: 4022776 (1977-05-01), Nakagawa et al.
patent: 4068076 (1978-10-01), Nakagawa et al.

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