Carbostyril derivatives

Details Carbostyril derivatives Carbostyril derivatives

1984-12-10

1986-06-03

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546158, A61K 3147, C07D21538

Patent

active

045930350

ABSTRACT:
Novel carbostyril derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen atom or a lower alkyl group, R.sup.2 is a lower alkyl group or a group of the formula: ##STR2## R.sup.3 is a lower alkylthio group, a lower alkyl group, a lower alkoxy group, phenoxy group, a phenyl(lower)alkoxy group, a lower alkenyloxy group, a phenyl group which may have a substituent selected from a lower alkoxy and a lower alkylenedioxy group on the phenyl ring, or a group of the formula: --NR.sup.4 R.sup.5 (R.sup.4 and R.sup.5 are the same or different and are each hydrogen atom or a lower alkyl group), and X is oxygen atom or sulfur atom, provided that when R.sup.1 is hydrogen atom and R.sup.2 is the group of the formula: ##STR3## X is not oxygen atom and R.sup.3 is not a lower alkyl group, and a pharmaceutically acceptable salt thereof, which show excellent pharmacological activities, such as myocardial contract increasing activity and coronary blood flow increasing activity and are useful for the treatment of heart diseases such as congestive heart failure.

REFERENCES:
patent: 4415572 (1983-11-01), Tominaga
Otsuka-CA 95:150468j.
Ueda, CA 33:7797.sup.9.
Ueda, CA 49:12470.sup.c.

Affiliated with

Also associated with

Rating

Carbostyril derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbostyril derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbostyril derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1232984