Carbonyl stress-decreasing agent

Details Carbonyl stress-decreasing agent Carbonyl stress-decreasing agent

2007-01-30

2007-01-30

Richter, Johann R. (Department: 1616)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

C514S151000

Reexamination Certificate

active

10089789

ABSTRACT:
The present invention provides agents that decrease carbonyl stress comprising biguanides, such as metoformin. Through oral administration and such, the carbonyl stress-decreasing agents of the present invention are useful as drugs directly acting against carbonyl stress in vivo.

REFERENCES:
patent: 4028402 (1977-06-01), Fischer et al.
patent: 5928916 (1999-07-01), Keogh
patent: 5952356 (1999-09-01), Ikeda et al.
patent: 6117451 (2000-09-01), Kumar
patent: 6559188 (2003-05-01), Gatlin et al.
patent: 756847 (2003-01-01), None
patent: 1 108 434 (1999-08-01), None
patent: WO 00/10606 (2000-03-01), None
patent: WO 00/69466 (2000-11-01), None
Solomon, T. W. G. Organic Chemistry, 5th edn. John Wiley & Sons, Inc.: New York, 1992, pp. 701-704.
Miyata, T. et al. Kidney International, 1999, 55, pp. 389-399.
Ruggiero-Lopez, D. et al. Biochem. Pharmacol. 1999, 58, pp. 1765-1773.
Layton et al., “Factors Influencing the Immunogenicity of the Haptenic Drug Chlorhexidine in Mice Part I. Molecular Requirements for the Induction of igE and igG Anti-hapten Antibodies,”Molecular Immunology, 24(2): 133-141, 1987.
Ruggiero-Lopez et al., “Reaction of Metformin with Dicarbonyl Compounds. Possible Implication in the Inhibition of Advanced Glycation End Product Formation,”Biochemical Pharmacology, 58: 1766-1773, 1999.
Tanaka et al., “Inhibitroy Effect of Metformin on Formation of Advanced Glycation end Products,”Current Therapeutic Research, 58 (10) 693-697, 1997.
Yasuda et al., “Carbonyl Stress. A New Development of Advanced Glybonyl End Products,”Gendai Igaku45(2): 363-368, (English Abstract) 1997.
Lin and Jin, “Basis of Medical Pharmacology,” I:311-312, World Book Publishing Company, Beijing (1994) (English Translation).
Ruggiero et al., “Reaction of metformin with reduced sugars and dicarbonyl compounds”, Diabetologia (Supp. 1), 40:A310 (1997).
Song G., et al., Shenyang Chemical Industry 1:43-5, 1996.
Song G., et al., Silk 12:51-4, 1996.

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