Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-05-08
1999-03-09
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544359, 544360, 544361, 544362, 544363, C07D29518, A61K 31495
Patent
active
058801286
ABSTRACT:
Novel carbonyl piperazinyl and piperidinyl compounds and pharmaceutical compositions are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel carbonyl piperazinyl or piperidinyl compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.
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Chemical Abstracts No. 100:203138 & Registry No. 90126-04-8 of Shiozawa et. al., Chem. Pharm. Bull. (1984), vol. 32, No. 2, pp. 553-563.
Afonso Adriano
Baldwin John J.
Doll Ronald J.
Li Ge
Mallams Alan K.
Dees Jos,e G.
Majka Joseph T.
Pharmacopeia Inc.
Qazi Sabiha
Schering Corporation
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