Carbonyl compounds as inhibitors of histone deacetylase for...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C564S084000, C564S088000

Reexamination Certificate

active

10865743

ABSTRACT:
Disclosed herein are carbonyl compounds of Formula I, II, or III, and others as described herein.Also disclosed are methods of treating disease, such as cancer, neurological disorders, including polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, autoimmune diseases and cardiovascular conditions, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.

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patent: WO 02/069947 (2002-09-01), None
Venkatesan et al., 1998, CAS: 129:230641.
Fujiwara et al., 1975, CAS: 82:9982.

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