Carbon monoxide process for the production of alpha amino acids

Details Carbon monoxide process for the production of alpha amino acids Carbon monoxide process for the production of alpha amino acids

1984-07-06

1985-10-15

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562517, 562406, 562443, 562519, C07C 9900

Patent

active

045475903

ABSTRACT:
A process is disclosed for the synthesis of alpha-amino acid by first contacting the condensation product of an aldehyde or ketone and an amine or amide with a protic or Lewis acid solvent and carbon monoxide to form an intermediate reaction product, and then hydrolyzing the intermediate to yield a product comprising the alpha-amino acid. The reaction rate and product yield can be increased by the addition of a Group 1B metal oxide catalyst in the first step.

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