Carbomycin biosynthetic gene, designated carG, for use in strept

Details Carbomycin biosynthetic gene, designated carG, for use in strept Carbomycin biosynthetic gene, designated carG, for use in strept

1987-02-24

1990-08-28

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 91, 4351721, 4351723, 43525233, 43525235, 435320, 435886, 536 27, 935 9, 935 22, 935 38, 935 61, 935 73, 935 75, C12P 1962, C12P 1934, C12N 121, C12N 1552

Patent

active

049525026

ABSTRACT:
The carG gene of Streptomyces thermotolerans has been isolated and used to construct recombinant DNA expression vectors. The carG gene encodes the activities required for the biosynthesis of the 16-member cyclic lactone of carbomycin. The carG gene can be used not only to construct recombinant cells with an increased ability to produce carbomycin but also to construct recombinant cells with the ability to produce novel antibiotic compounds.

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