Carboline derivatives as PDE5 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C544S099000, C544S184000, C544S343000, C546S070000, C514S243000, C514S250000, C514S285000

Reexamination Certificate

active

06984641

ABSTRACT:
Selective inhibitors of cGMP-specific PDE, and use of the compounds and salts and solvates thereof as therapeutic agents, are disclosed.

REFERENCES:
patent: 5218119 (1993-06-01), Kreidl et al.
patent: 5747520 (1998-05-01), Pommier et al.
patent: 6143746 (2000-11-01), Daugan et al.
patent: WO 95/19978 (1995-07-01), None
patent: WO 97/03985 (1997-02-01), None
patent: WO 97/43287 (1997-11-01), None
patent: WO 00/15639 (2000-03-01), None
patent: WO 01/87038 (2001-11-01), None
patent: WO 01/94347 (2001-12-01), None
patent: WO 02/28859 (2002-04-01), None
Edmund Sybetz et al., “Inhibitors of PDE1 and PDE5 cGMP Phosphodiesterases: patents and therapeutic potential”,Expert Opinion on Therapeutic Patents, 7(6):631-639 (1997).

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