Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Chemical aftertreatment – e.g. – acylation – methylation – etc.
Reexamination Certificate
2006-11-21
2006-11-21
Tsang, Cecilia J. (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Chemical aftertreatment, e.g., acylation, methylation, etc.
Reexamination Certificate
active
07138491
ABSTRACT:
The present invention relates to the protected intermediates and the deprotected products of P6A, related to the protected pseudopeptides introducing the protected intermediateds of P6A to 3S-(2-Boc)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid and the deprotected pseudopeptides, related to the protected pseudopeptides introducing the protected intermediateds of P6A to 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid benzyl ester, related to the methods for their preparation, and related to their use as the thrombolytic agents.
REFERENCES:
patent: 1373139 (2002-10-01), None
Wu et al, Synthesis and Thrombolytic Activity of Pseudopeptides Related to Fibrinogen Fragment, Bioorganic & Medicinal Chemistry Letters, vol. 12 Sep. (2002), pp. 2331-2333.
Wu Y, Zhao M, Wang C, Peng S Synthesis and thrombolytic activity of pseudopeptides related to fibrinogen fragment.Bioorg Med Chem Lett. Sep. 2, 2002; 12(17):2331-3.
Peng Shiqi
Wang Chao
Wu Yangfen
Zhao Ming
Finnegan Henderson Farabow Garrett & Dunner LLP
Guangzhou Bai Yun Shan Pharmaceutical Co., Ltd.
Heard Thomas S.
Tsang Cecilia J.
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