Carbohydrate prodrugs of fluorooxindoles

Details Carbohydrate prodrugs of fluorooxindoles Carbohydrate prodrugs of fluorooxindoles

2005-07-12

2005-07-12

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S419000, C514S043000, C536S017400

Reexamination Certificate

active

06916937

ABSTRACT:
The present invention provides novel prodrug derivatives of fluorooxindoles having the general Formula Iwherein the wavy bond (img id="CUSTOM-CHARACTER-00001" he="2.46mm" wi="4.23mm" file="US06916937-20050712-P00001.TIF" alt="custom character" img-content="character" img-format="tif" ?) represents the racemate, the (R)-enantiomer or the (S)-enantiomer, and R1, R2, R3, R4and X are as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are responsive to the opening of potassium channels.

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