Carbohydrate mimetics having antiadhesive properties

Details Carbohydrate mimetics having antiadhesive properties Carbohydrate mimetics having antiadhesive properties

1997-07-28

2000-10-24

Fonda, Kathleen K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 23, 514 54, 514 61, 514 62, 536 41, 536 172, 536 175, 536 185, 536 186, 536 187, 536 33, 536 53, 536 54, 536 55, 536 551, 536 552, 536 553, 536118, 536124, A61K 3170, C07H 1500

Patent

active

061367907

ABSTRACT:
The invention relates to carbohydrate mimetics, which inhibit the binding of selectin to carbohydrate ligands, of the formula I ##STR1## excluding the compounds sialyl-Lewis-X and -A and their derivatives which, instead of an N-acetyl group, carry the substituents N.sub.3, NH.sub.2 or OH or which, instead of fucose, carry glycerol,
and pharmaceutical compositions and diagnostic agents containing these derivatives, and methods for using these pharmaceutical compositions and diagnostic agents.

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