Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-08-21
2007-08-21
Chan, Christina (Department: 1644)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007920, C435S070210, C435S810000, C530S388100, C530S388150, C530S388250
Reexamination Certificate
active
10612162
ABSTRACT:
The present invention relates to antibodies which, in agueous solution, selectively bind to a transferrin-homologous carbohydrate deficient transferrin (CDT) without the latter needing to be bound to a solid phase. CDT is characterized by at least one of the two oligosaccharide chains which are normally bound to Asn 413 and/or Asn 611 of transferrin being entirely or substantially entirely lacking.
REFERENCES:
patent: 5702904 (1997-12-01), Makhlouf et al.
patent: 0 605 627 (1994-07-01), None
patent: 93/06133 (1993-04-01), None
patent: 99/00672 (1999-01-01), None
patent: 00/36418 (2000-06-01), None
Kuby et al, Immunology, Second edition, pp. 86-96, 1994.
Abaza et al, J of Protein Chemistry 11(5): 433-444, 1992.
Duan et al., Generation of Carbohydrate-Deficient Transferrin by Enzymatic Deglycosylation of Human Transferrin,Applied Biochemistry and Biotechnology, 69:217-224 (1998).
Mason et al., “Expression of Glycosylated and Nonglycosylated Human Transferrin in Mammalian Cells. Characterization of the Recombinant Proteins with Comparison to Three Commerically Available Transferrins,”Biochemistry, 32:5472-5479 (1993).
Messerschmid, “Erzeugung von polyklonalen Antikörpern in Nicht-Säugern,”BIOforum Forschung und Entwicklung, 19:500-502 (1996) (English Abstract).
Wenschuh et al., “Coherent Membrane Supports for Parallel Microsynthesis and Screening of Bioactive Peptides,”Biopolymers, 55:188-206 (2000).
Wilson et al., “Recent Developments in the Periodate Method of Conjugating Horseradish Peroxidase (HRPO) to Antibodies,” In:Immunofluorescence and Related Staining Techniques, pp. 215-224 (1978).
Trimble et al., “Anti-Peptide Antibodies to Epitopes Masked by the Carbohydrate Moieties in Transferrin,”Biochemical Society Transactions, 26:S48 (1998).
Althaus et al., “Development and Evaluation of a New Carbohydrate-Deficient Transferrin (CDT)-Specific Monoclonal Antibody,”Clinical Chemistry, 49(6):A113 (2003).
Chan Christina
Dade Behring Marburg GmbH
Finnegan, Henderson Farabow, Garrett and Dunner L.L.P.
Huynh Phuong
LandOfFree
Carbohydrate deficient transferrin (CDT) -specific... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Carbohydrate deficient transferrin (CDT) -specific..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbohydrate deficient transferrin (CDT) -specific... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3838405