Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-02-05
1996-07-30
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 514 25, 514 53, 514 54, 514 61, 4242651, G01N 33569, A61K 3170
Patent
active
055410758
ABSTRACT:
The present invention relates to Trichinella vaccines that include at least one tyvelose-containing oligosaccharide or functional equivalent thereof, to Trichinella vaccines that include at least one fucose-containing oligosaccharide or functional equivalent thereof, and to the use of such vaccines to protect animals from Trichinella infections, and particularly from trichinosis caused by Trichinella spiralis infection. Such vaccines can also be used to produce antibodies that are capable of protecting an animal from Trichinella infections and of diagnosing such infections. The present invention also relates to Trichinella diagnostic reagents that include at least one tyvelose-containing oligosaccharide, or functional equivalent thereof, and use of such reagents to detect Trichinella, and particularly Trichinella spiralis infections. The present invention also includes diagnostic kits based on such reagents and anti-Trichinella-spiralis drugs based on the knowledge that tyvelose is produced by Trichinella spiralis parasites.
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Grieve Robert B.
McNeil Michael R.
Wassom Donald L.
Wisnewski Nancy
Heska Corporation
Housel James C.
Krsek-Staples Julie
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