Carbocyclic nucleosides containing bicyclic rings, oligonucleoti

Details Carbocyclic nucleosides containing bicyclic rings, oligonucleoti Carbocyclic nucleosides containing bicyclic rings, oligonucleoti

1995-06-06

1997-03-11

Tsang, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

564460, 544229, 544311, 544312, 544313, 544314, 544317, 544318, 544323, 544325, 544329, 544243, 546118, C07F 902, C07D47300, C07D23902, A61K 31695

Patent

active

056103000

ABSTRACT:
Compounds of the formulae I and Ia and their racemates ##STR1## in which A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 --, R.sub.1 is hydrogen or a protective group, R.sub.2 is hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide bridge group and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for the preparation of biologically active oligonucleotides.

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