Carbocyclic nucleosides containing bicycle rings, oligonucleotid

Details Carbocyclic nucleosides containing bicycle rings, oligonucleotid Carbocyclic nucleosides containing bicycle rings, oligonucleotid

1993-06-28

1995-10-24

Tsang, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544243, 544244, 544276, 544277, 544264, 544311, 544312, 544313, 544314, 544317, 544318, 544323, 544325, 544329, 514 63, 514 81, 514 86, 514258, 514269, 514274, 514303, 546118, 564460, C07F 902, C07D47300, C07D23902, A61K 31695

Patent

active

054611520

ABSTRACT:
Compounds of the formulae I and Ia and their racemates ##STR1## in which A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 --, R.sub.1 is hydrogen or a protective group, R.sub.2 is hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide bridge group and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for the preparation of biologically active oligonucleotides.

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