Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1979-07-17
1980-11-04
Berch, Mark L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
C07D23946, C07D49804, A61K 31505
Patent
active
042321549
ABSTRACT:
Novel compounds are disclosed which are carbocyclic analogs of cytosine nucleosides in which the pentose moiety of the nucleoside is replaced by a cyclopentane ring. The novel compounds exhibit antiviral activity, and certain of them also exhibit antineoplastic activity against the L 1210 mouse leukemia test system.
REFERENCES:
patent: 3040026 (1972-06-01), Duschinsky
Shealy et al.I,J.Pharm. Sci. 62, 1252 (1973).
Shealy et al. II, J. Pharm. Sci. 62, 858 (1973).
Shaeffer et al. I, J. Org. Chem. 25, 774 (1960).
Shealy et al. III, J. Amer. Chem. Sci. 91, 3075 (1969).
Kishi et al. Chem. Comm. 1967, 852.
Shealey et al. VI, Tet. Letters 1969, 2231-2234 (1969).
Shaeffer et al. II, J. Pharm. Sci. 53, 1510 (1964).
Shealey et al. V, J. Amer. Chem. Soc. 88, 3885 (1966).
Cook et al., J. Het. Chem. 15, 1-8 (1978).
Shealey et al. VI, J. Het. Chem. 10, p. 601 (1973).
Murdock et al. J. Amer. Chem. Soc. 84,3758 (1962).
Shealey et al. VII, J. Het. Chem. 13, 1015-1020 (1976).
Oxfard Chem. Dictionery vol. 2, pp. 809, 837.
Shealey et al. VIII, Chem. Abs. 90, 39151h (1978).
O'Dell C. Allen
Shealy Y. Fulmer
Berch Mark L.
United States of America
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