Carbene porphyrins and carbene porphyrinoids, methods of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S410000

Reexamination Certificate

active

06919448

ABSTRACT:
The present invention includes novel N-heterocyclic carbene substituted porphyrins and porphyrinoids. The invention also includes complexes of metals and N-heterocyclic carbene substituted porphyrins and porphyrinoids. The invention further includes N-heterocyclic carbene substituted porphyrins and porphyrinoids, and metal complexes of N-heterocyclic carbene substituted porphyrins and porphyrinoids that also includes a targeting moiety or group. The compositions of the present invention are useful in the fields of diagnosis and treatment of many medical ailments.

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patent: 6025496 (2000-02-01), Herrmann et al.
Arduengo, Anthony J., III et al, “Electronic Stabilization of Nucleophilic Carbenes.”J. Am. Chem. Soc., vol. 114, pp. 5530-5534 (1992).
Arduengo, Anthony J., III et al. “Homoleptic Carbene-Silver (I) and Carbene-Copper(I) Complexes.”Organometallics, vol. 12, pp. 3405-3409. (1993).
Arduengo, Anthony J., III et al. “Imidazolylidenes, Imidazolinylidenes and Imidazolidines.”Tetrahedron, vol. 55, pp. 14523-14534 (1999).
Garrison, Jered C. et al. “Synthesis and Structural Characterization of a Silver Complex of a Mixed-Donor N-Heterocyclic Carbene Linked Cyclophane.”Chem. Commun., pp. 1780-1781 (2001).

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