Carbazole inhibitors of Cox-2

Details Carbazole inhibitors of Cox-2 Carbazole inhibitors of Cox-2

1998-03-16

1998-10-20

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548443, 548444, 548447, 548449, A61K 3140, C07D20982

Patent

active

058246991

ABSTRACT:
This invention provides compounds of formula I having the structure ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are, each, independently, hydrogen, alkyl, alkenyl, alkynyl, alkoxy, aralkoxy, trifluroalkoxy, alkanoyloxy, hydroxy, halo, trifluoromethyl, cyano, amino, mono- or di-alkylamino, alkanamido, or alkanesulfonamido;

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