Carbapenem derivatives, their preparation and their use as antib

Details Carbapenem derivatives, their preparation and their use as antib Carbapenem derivatives, their preparation and their use as antib

1995-06-06

1998-01-27

Cook, Rebecca

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540350, C07D48704, A61K 3140

Patent

active

057122679

ABSTRACT:
Compounds of formula (I): ##STR1## wherein R.sup.1x is hydrogen or methyl, R.sup.2x is hydrogen optionally substituted aliphatic hydrocarbon or acylimidoyl, R.sup.3x is hydrogen or an ester group, and Q.sup.x is cyclic or acyclic nitrogen-containing group. The compounds are potent antibiotics which are resistant to dehydropeptidase I, and are thus useful for the treatment of many microbial infections.

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patent: 5122604 (1992-06-01), Sunagawa et al.
patent: 5310735 (1994-05-01), Kawamoto et al.
patent: 5420119 (1995-05-01), Kawamoto
Chemical Abstracts, vol. 117, 1992, Columbus, Ohio, US, "Preparation of carbapenem derivatives and their salts as antibiotics," abstract No. 69658X of JP-A-92 36,282.

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