Carbapenem derivatives having antibiotic activity, their prepara

Details Carbapenem derivatives having antibiotic activity, their prepara Carbapenem derivatives having antibiotic activity, their prepara

1992-08-31

1994-05-10

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540350, A01N 4300, A61K 31395, C07D48704

Patent

active

053107357

ABSTRACT:
Carbapenem compounds of formula (I): ##STR1## in which: A is a fully saturated heterocyclic group, of which at least one ring atom is nitrogen; R.sup.1 is hydrogen or methyl; R.sup.2 is hydrogen or alkyl; R.sup.3 is hydrogen or a negative ion; Q is: (i) --B--N.sup.+ R.sup.8 R.sup.9 R.sup.10, where R.sup.8, R.sup.9 and R.sup.10 are alkenyl, alkynyl or optionally substituted alkyl, and B is alkylene or alkylidene.

REFERENCES:
patent: 3950357 (1976-04-01), Kahan et al.
patent: 4194047 (1980-03-01), Kahan et al.
patent: 4552873 (1985-11-01), Miyadera et al.
patent: 4771046 (1988-09-01), Kawamoto et al.
patent: 5227376 (1993-07-01), Sunagawa et al.
Kim et al, J Med Chem, 1989, 32, 601-604.

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