Carbapenem derivatives

Details Carbapenem derivatives Carbapenem derivatives

1982-09-29

1985-12-03

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D48704, A61K 3140

Patent

active

045565171

ABSTRACT:
A compound of the formula: ##STR1## wherein R is carboxymethylthio, dihydroxymethylthio or hydroxymethylsulfinyl and the pharmaceutically acceptable salts being useful as a medicament and a veterinary drug for inhibiting the growth of gram-positive and gram-negative phathogenic microorganisms with .beta.-lactamase inhibitory activity and a process for preparing the same.

REFERENCES:
patent: 4150145 (1979-04-01), Christensen et al.
patent: 4347181 (1982-08-01), Smale
patent: 4473578 (1984-09-01), Corbett
Tsuji et al., Jour. of Antibiotics, vol. XXXV, No. 4, pp. 536-540, (1982).

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