Carbapenem compounds and their production

Details Carbapenem compounds and their production Carbapenem compounds and their production

1981-02-20

1983-10-11

Lee, Mary C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424274, C07D48704

Patent

active

044091478

ABSTRACT:
Novel carbapenem compounds, which are shown by the formula (I): ##STR1## wherein R is --SO.sub.3 H or hydrogen, or a physiologically acceptable salt thereof, are useful as a bactericide or disinfectant, and also produce a synergistic effect with penicillin and/or cephalosporin antibiotic agents.
The compound of the formula (I) can be produced by subjecting to reduction reaction a compound of the formula: ##STR2## wherein R has the same meaning as defined above, or a salt thereof.

REFERENCES:
patent: 4141986 (1979-02-01), Cassidy et al.
patent: 4162323 (1979-07-01), Kahan
patent: 4189473 (1980-02-01), Cole et al.
patent: 4210661 (1980-07-01), Ponsford et al.
patent: 4223038 (1980-09-01), Smale
patent: 4341705 (1982-07-01), Shih
patent: 4341706 (1982-07-01), Christensen et al.
Harada et al.; J. of Antibiotics; vol. 33, pp. 1425-1430, (12/1980).

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