Carbapenem antibiotics

Details Carbapenem antibiotics Carbapenem antibiotics

1983-03-08

1985-11-12

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D48704, A61K 3140

Patent

active

045526966

ABSTRACT:
Disclosed are novel carbapenem derivatives characterized by a 2-substituent of the formula ##STR1## in which A represents cyclopentylene, cyclohexylene or C.sub.2 -C.sub.6 alkylene optionally substituted by one or more C.sub.1 -C.sub.4 alkyl groups and ##STR2## represents a quaternized nitrogen-containing aromatic heterocycle. Such derivatives are useful as potent antibacterial agents. Also disclosed are processes for the preparation of such derivatives and novel intermediates utilized in these processes.

REFERENCES:
patent: 4235920 (1980-11-01), Christensen et al.

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