Carbapenem antibiotics

Details Carbapenem antibiotics Carbapenem antibiotics

1985-08-19

1987-02-10

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540302, C07D48704, A61K 3140

Patent

active

046423419

ABSTRACT:
Disclosed are novel carbapenem derivatives characterized by a 2-substituent of the formula ##STR1## in which A represents cyclopentylene, cyclohexylene or C.sub.2 -C.sub.6 alkylene optionally substituted by one or more C.sub.1 -C.sub.4 alkyl groups and ##STR2## represents a quaternized nitrogen-containing aromatic heterocycle. Such derivatives are useful as potent antibacterial agents. Also disclosed are processes for the preparation of such derivatives and novel intermediates utilized in these processes.

REFERENCES:
patent: 4150145 (1979-04-01), Christensen et al.
patent: 4189493 (1980-02-01), Christensen et al.
patent: 4218463 (1980-08-01), Christensen et al.
patent: 4226870 (1980-10-01), Christensen et al.
patent: 4234596 (1980-11-01), Christensen et al.
patent: 4235917 (1980-11-01), Christensen et al.
patent: 4235920 (1982-11-01), Christensen et al.
patent: 4269772 (1981-05-01), Melillo et al.
patent: 4273709 (1981-06-01), Christensen et al.
patent: 4282148 (1981-08-01), Liu et al.
patent: 4287123 (1981-09-01), Liu et al.
patent: 4290947 (1981-09-01), Christensen et al.
patent: 4309346 (1982-01-01), Christensen et al.
patent: 4318912 (1982-03-01), Christensen et al.
patent: 4552696 (1983-03-01), Kim et al.
Leanza, et al., Recent Advances in the Chemistry of .beta.-Lactam Antibiotics, 1981, pp. 240-254, Royal Society of Chemistry, London.
Gordon Research Conference Handout, Aug. 2-6, 1982, New London, New Hampshire, p. 9.

Affiliated with

Also associated with

Rating

Carbapenem antibiotics does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbapenem antibiotics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbapenem antibiotics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2363168