Carbapenem

Details Carbapenem Carbapenem

1995-06-02

1997-03-25

Cook, Rebecca

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07D48704

Patent

active

056146248

ABSTRACT:
A compound of the formula ##STR1## in which: R.sup.1' is hydrogen or a carboxy-protecting group;

REFERENCES:
patent: 4772683 (1988-09-01), Martel et al.
patent: 4820817 (1989-04-01), Christensen
patent: 4895939 (1990-01-01), Martel et al.
patent: 5011832 (1991-04-01), Dininno et al.
McOmie, Protective Groups in Organic Chemistry, 1973, pp. 183-210.
Sown, et al, "Enantioselective Synthesis of the 1.beta.-Methylcarbapenems via Cycloaddition of 3-Siloxypentadiene and 4-Acetoxyazetidinone", J.A.C.S., 53, 4154 (1988).
Guthikonda et al, "Structure-Activity Relationships in the 2-Arylcarbapenem Series: Synthesis of 1-Methyl-2-arylcarbapenems", J. Med. Chem., 30, 871 (1987).
Kim et al, "Stereoselective Synthesis of 1-.beta.-Methylcarbapenem", Tetrahedron Letters, 28, 507-510 (1987).

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