Carbamoyloxyamino-1,4-benzodiazepines and medicaments containing

Details Carbamoyloxyamino-1,4-benzodiazepines and medicaments containing Carbamoyloxyamino-1,4-benzodiazepines and medicaments containing

1981-06-02

1983-07-26

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260239BD, 2602393D, 546272, 424263, C07D24320, A61K 3155

Patent

active

043954090

ABSTRACT:
What are disclosed are 1,4-benzodiazepines, having a carbamoyloxyamino group, of the following formula I ##STR1## tautomers thereof of the following formula IA ##STR2## physiologically tolerated salts thereof, said compounds having an anxiolytic action without sedating, a process for the preparation of these new compounds, pharmaceutical agents which contain the active compounds, and methods for treating anxiety states with said compounds.

REFERENCES:
patent: 3205223 (1965-09-01), Bell
patent: 3268586 (1966-08-01), Berger et al.
patent: 3649617 (1972-03-01), Hester
patent: 3678036 (1972-07-01), Archer et al.
patent: 3799920 (1974-03-01), Ferrari et al.
patent: 3825533 (1974-07-01), Nudelman et al.
patent: 3896109 (1975-07-01), Hester
patent: 4235897 (1980-11-01), Demarne et al.
patent: 4325957 (1982-04-01), Zeugner et al.
Hester and Rudzik, "Benzodiazepines", J. Med. Chem., vol. 17, pp. 293-295, (1974).
Wagner and Zook, Synthetic Organic Chemistry, (1953), p. 645.

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