Carbamoylation of amino groups in peptides via N-aryloxycarbonyl

Details Carbamoylation of amino groups in peptides via N-aryloxycarbonyl Carbamoylation of amino groups in peptides via N-aryloxycarbonyl

1994-06-22

1998-06-23

Lukton, David

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Synthesis of peptides

530335, 530337, 530345, C07K 1107

Patent

active

057706921

ABSTRACT:
Method of synthesising peptides containing one or more amino acid residues bearing an N-carbamoyl functional group, by aminolysis of N-aryloxycarbonyl derivatives, which are excellent synthesis intermediates for the preparation of various peptides containing amino acid residues bearing a ureino group, such as citrulline, homocitrulline, 2-amino-4-ureidobutyric residues.

REFERENCES:
patent: 3928305 (1975-12-01), Werle
patent: 4725645 (1988-02-01), Anteunis et al.
patent: 4980284 (1990-12-01), Makryaleas
patent: 5198533 (1993-03-01), Schally
Izdebski, Synthesis 423, 1989 Madelmont J Med Chem 28, 1346 ('85).
Jaffe Chem Reviews 53, 191-261, 1953.
March, Adv Org Chem, 278-286, 1992.
Charton Chemtech 5, 245-255, 1975.
Charton Chemtech 4 502-511.
Lehninger, A.E., Biochemistry, 2nd edition, 1975, p. 149.
Boissonnas et al, Helvetica Chimica Acta, vol. 36, No. 4, 1953, pp.
Houben-Weyl, Methoden Der Organischen Chemie, 4th Ed., vol. XV, No. 1, p. 472.

Affiliated with

Also associated with

Rating

Carbamoylation of amino groups in peptides via N-aryloxycarbonyl does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbamoylation of amino groups in peptides via N-aryloxycarbonyl, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbamoylation of amino groups in peptides via N-aryloxycarbonyl will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1395440