Carbamoyl substituted heterocycles

Details Carbamoyl substituted heterocycles Carbamoyl substituted heterocycles

1998-09-04

2000-06-13

Fan, Jane

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546194, 544131, C07D41310

Patent

active

060751479

ABSTRACT:
This invention relates to carbamoyl substituted heterocycles which are .omega.-phenyl-.omega.-(3-pyridyl)-.omega.-alkenoic acid derivatives bearing a carbamoyl substituted oxazolyl or oxazolinyl group on the phenyl ring and which demonstrate utility for thromboxane receptor antagonism and/or thromboxane synthase inhibition, as well as pharmaceutical formulations containing them, methods for their use, and processes and intermediates for their preparation.

REFERENCES:
patent: 4980478 (1990-12-01), Hatanaka et al.
patent: 5100889 (1992-03-01), Misra et al.
patent: 5153327 (1992-10-01), Misra et al.
patent: 5158967 (1992-10-01), Hall
patent: 5162352 (1992-11-01), Hall et al.
Misra, R.N., et al., Bioorg. & Med. Chem. Letters, 1, 461-464, (1994).
Misra, R.N., et al., Bioorg. & Med. Chem. Letters, 1, 465-470, (1991).
Misra, R.N., et al., Bioorg. & Med. Chem. Letters, 2, 73-76, (1992).
Vermylen, J., et al., Cardiovascular Drugs and Therapy, 6, 29-33, (1992).
Soyka, R., et al., J. Med. Chem., 37, 26-39, (1994).
Takeuchi, K., et al., Bioorg. & Med. Chem. Letters, 2, 743-755, (1994).
Ishikura, M., et al., Heterocycles, 22(11), 2475-2478 (1984).
Negishi, E., et al., Heterocycles, 18, 117-122 (1982).
Sakamoto, T., et al., Heterocycles, 31(2), 219-221, (1990).
Parrain, et al., Tetrahedron Letters, 31(13), 1857-1860, (1990).

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