Carbamic acid derivatives as selective immunosuppresive agents

Details Carbamic acid derivatives as selective immunosuppresive agents Carbamic acid derivatives as selective immunosuppresive agents

1979-08-08

1984-05-22

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424270, A61K 3154, A61K 31425

Patent

active

044501595

ABSTRACT:
Novel cyclized .omega.-carboxyethyl mono or dithiocarbanilic acids are disclosed as immunoregulatory agents, useful in the treatment of organ transplant reject phenomenon and autoimmune diseases particularly where a delayed hypersensitivity component has been established, such as multiple sclerosis.
Additionally described is the use of certain cyclized .omega.-carboxyalkyl mono- or dithiocarbamic acids and certain cyclized .omega.-carboxyalkyl mono- or dithiocarbamic acids.

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The Merck Manual, 10th ed., 1961, pp. 1104, 1479 & 1480.

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