Carbamazepine derivatives used in particle reagents

Details Carbamazepine derivatives used in particle reagents Carbamazepine derivatives used in particle reagents

1997-04-03

1998-11-03

Nutter, Nathan M.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is organic

436534, 436108, C07D22322, G01N 33546

Patent

active

058307680

ABSTRACT:
The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention also provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has the following general structure: ##STR2## where X is C.dbd.O, CH.sub.2 or SO.sub.2 ; Y is C.dbd.O, CH.sub.2, SO.sub.2 ; R is an alkyl and P is a protein or a hapten.

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Wang, et al., Chemical Abstracts; Reagents and Method for Determining Ligands in a Sample of Biological Liquids; 98:2496; 1983.

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