Carbamates related to (-)-physostigmine as cholinergic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548429, A61K 3140, C07D48700

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active

049007483

ABSTRACT:
Highly potent analogs of (-)-physostigmine are provided which are potent inhibitors of acetylcholinesterase and butyrylcholinesterase. These compounds are useful in treatment of glaucoma, Alzheimer's disease, myasthenia gravis, and organophosphate poisoning.

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Chemical Abstracts 105:72467s (1986).

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