Carbamates of rapamycin

Details Carbamates of rapamycin Carbamates of rapamycin

1995-03-13

1996-09-24

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

540456, A61K 31675, A61K 31395, C07D49106

Patent

active

055591205

ABSTRACT:
A compound of the structure ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, A, B and Ar are all defined in the body of the specification or a pharmaceutically acceptable salt thereof which is useful as an immuno-suppressive, antiinflammatory, antifungal, antiprliferative and antitumor agent.

REFERENCES:
patent: 3929992 (1975-12-01), Sehgal et al.
patent: 3993749 (1976-11-01), Sehgal et al.
patent: 4316885 (1982-02-01), Rakhit
patent: 4375464 (1983-03-01), Sehgal et al.
patent: 4401653 (1983-08-01), Eng
patent: 4650803 (1987-03-01), Stella et al.
patent: 4885171 (1989-12-01), Surendra et al.
patent: 5023262 (1991-06-01), Caufield et al.
patent: 5023263 (1991-06-01), Von Burg
patent: 5023264 (1991-06-01), Caufield et al.
patent: 5078999 (1992-01-01), Warner et al.
patent: 5080899 (1992-01-01), Sturm et al.
patent: 5091389 (1992-02-01), Ondeyka et al.
patent: 5100883 (1992-03-01), Schiehser
patent: 5100899 (1992-03-01), Calne
patent: 5102876 (1992-04-01), Caufield
patent: 5118677 (1992-06-01), Caufield
patent: 5118678 (1992-06-01), Kao et al.
patent: 5120842 (1992-06-01), Failli et al.
patent: 5130307 (1992-07-01), Failli et al.
patent: 5138051 (1992-08-01), Hughes et al.
patent: 5151413 (1992-09-01), Caufield et al.
patent: 5169851 (1992-12-01), Hughes et al.
patent: 5177203 (1993-01-01), Failli et al.
patent: 5194447 (1993-03-01), Kao
patent: 5221670 (1993-06-01), Caufield
patent: 5233036 (1993-08-01), Hughes
patent: 5260300 (1993-11-01), Hu
patent: 5262423 (1993-11-01), Kao
patent: 5286730 (1994-02-01), Caufield et al.
patent: 5286731 (1994-02-01), Caufield et al.
patent: 5302584 (1994-04-01), Kao et al.
Venzina, C., J. Antibiot. 28:721 (1975).
Sehgal, S. N., J. Antibiot. 28:727 (1975).
Baker, H. J., Antibiot. 31:539 (1978).
Martel, R. R., Can. J. Physiol. Pharmacol. 55:48 (1977).
Staruch, M. J., FASEB 3:3411 (1989).
Dumont, F. J., FASEB 3:5256 (1989).
Calne, R. Y., Lancet 1183 (1978).
Morris, R. E., Med. Sci. Res. 17:877 (1989).
Baeder, W. L., Fifth Int. Conf. Inflamm. Res. Assoc. 121 (Abstract) (1990).
Meiser, B. M., J. Heart Lung Transplant. 11 (pt. 2):197 (1992).
Stepkowski, S. M., Transplantation Proc. 23:507 (1991).

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