Carbamates of rapamycin

Details Carbamates of rapamycin Carbamates of rapamycin

1995-02-27

1996-07-02

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07D49816, A61K 31395

Patent

active

055323553

ABSTRACT:
A compound of the structure ##STR1## wherein R and R.sup.1 are each, independently, hydrogen, ##STR2## R.sup.2 and R.sup.3 are each, independently, hydrogen, alkyl, alkenyl, alkynyl, --CO.sub.2 R.sup.5, --COR.sup.5, --CN, --NO.sub.2, --SO.sub.2 R.sup.5, --SO.sub.3 R.sup.5, --OR.sup.5, --SR.sup.5, or Ar;

REFERENCES:
patent: 3929992 (1975-12-01), Sehgal et al.
patent: 3993749 (1976-11-01), Sehgal et al.
patent: 4316885 (1982-02-01), Rakhit
patent: 4401653 (1983-08-01), Eng
patent: 4650803 (1987-03-01), Stella et al.
patent: 4885171 (1989-12-01), Sehgal et al.
patent: 5078999 (1992-01-01), Warner et al.
patent: 5080899 (1992-01-01), Sturm et al.
patent: 5091389 (1992-02-01), Ondeyka et al.
patent: 5100883 (1992-03-01), Schiehser
patent: 5100899 (1992-03-01), Calne
patent: 5118677 (1992-06-01), Caufield
patent: 5118678 (1992-06-01), Kao et al.
patent: 5130307 (1992-07-01), Failli et al.
patent: 5194447 (1993-03-01), Kao
Vezina, C., J. Antibiot. 28, 721-726 (1975).
Sehgal, S. N., J. Antibiot. 28, 727-732 (1975).
Baker, H., J. Antibiot. 31, 539-545 (1978).
Martel, C., Can J. Physiol. Pharmacol. 55, 48 (1977).
Staruch et al., FASEB 3,3441 (1989).
Dumont, F., FASEB 3, 5256 (1989).
Calne et al., Lancet, 1183-1185 (1978).
Morris, R., Med. Sci. Res. 17:877 (1989).
Baeder, W. L. Fifth Int. Conf. Inflamm. Res. Assoc. 121 (Abstract) (1990).
Meiser, B. M., J. Heart Lung Transplant 11 (pt2): 197 (1992).

Affiliated with

Also associated with

Rating

Carbamates of rapamycin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbamates of rapamycin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbamates of rapamycin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1507372